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Drug-Allergy Interaction (DAI) Alert

Updated: 06/27/2025|Views: 2102

Clinical enables medical professionals to write prescriptions for drugs, durable medical equipment (DME), or supplies that can be printed for the patient or sent electronically to the pharmacy. With each new medication prescribed, Clinical automatically checks for, and alerts you to, the potential for significant drug-drug interactions or allergic reactions.

A Drug-Allergy Interaction alert message appears when a prescribed drug has the potential to interact with an allergen listed in a patient's allergy profile. There are three Drug-Allergy Alert security levels: Severe, Moderate, and Mild. Based on your Drug-Allergy Alert notification settings, you have the following choices when an alert appears: 

Create Prescription

  1. Enter the first 2–3 letters of the patient's name or date of birth (mm/dd/yyyy) in the top navigation bar search box.
  2. Click to select the patient from the auto-populated results. The patient's Facesheet page opens.
  3. Click Medications. The Active Medications page opens.
  4. Click + Prescription. The Prescribe Medication page opens.
  5. Prescribe the medication. The Drug- Allergy Alert pop-up window opens.
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Review Drug-Allergy Alert

  1. Review Interaction Details:
    • Existing Allergy: The patient's allergen that interacts with the medication being prescribed.
    • Severity Level: Displays the interaction severity level (e.g., mild, moderate).
    • Interaction Type: Displays the interaction type (e.g., drug-allergy)
    • DAI Severity Details: Click the down arrow to display information about the drug-allergy interaction.
  2. Override Reason: If applicable, click to select the reason(s) to override the alert to continue prescribing the selected medication.
    Note: Based on the practice's Allergy Interaction notification settings, an override reason may not be required to continue prescribing.
  3. Click Apply Override Reason.
  4. Click Submit to continue prescribing the medication.
    • To clear the prescription fields and prescribe a new medication, click Cancel Rx.
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