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ePrescribe Controlled Substance (EPCS)

Updated: 06/05/2025|Views: 34057

Clinical offers medical professionals the ability to write prescriptions for controlled substances that can be printed for a patient or sent to a pharmacy electronically. With each new medication, Clinical automatically checks for and alert the prescriber of any drug-drug interactions and allergic reactions.

EPCS enrollment is required for providers to send controlled substances electronically.

Access Patient Medications

  1. Enter the first 2–3 letters of the patient's name or date of birth (mm/dd/yyyy) in the top navigation bar search box.
  2. Click to select the patient from the auto-populated results. The patient's Facesheet page opens.
  3. Click Medications. The Active Medications page opens.
Clinical_Medications_Access.png

Prescribe Medication

For practices on the legacy medication ordering experience, click Try it Out to prescribe using the new medication ordering experience.

  1. Click + Prescription. The Prescribe Medication page opens.
  2. Drug: Enter the name of the drug, DME, or supplies to return a list of matching results with the applicable dosage and dispense forms. Select the desired result from the list.
    Tip_Icon.png Tip: When the desired drug is not listed, enter additional drug information (e.g., generic drug name, entire drug name, "ER" for extended release drugs, dosage, or dispense form) to narrow the search.
    • If the desired drug is not listed, click to select "Advanced Search". Enter the name of the drug, DME, or supply to return a list of matching results with the available dispensable drugs and the brand name or generic form of the drug. Select the desired result from the list.
    • To prescribe a drug favorite, click in the Drug Name field and select the drug favorite.
  3. Quantity: Click the drop-down and select from available quantity options for the drug or enter a custom quantity. The unit description of the selected drug displays to the right of the Quantity amount.
    • To indicate a partial dispensing, enter a decimal value leading with a zero (e.g., "0.5") as the Quantity.
    • When applicable, the Total quantity displays based on the calculation of the drug's pre-determined manufactured unit size multiplied by the quantity amount entered. For example, if prescribing a packet of 30 tablets and the quantity is 10, the total amount of prescribed tablets is 300.
  4. Refill: Click the drop-down and select the number of refills for the prescription.
    • By default, "Allow Substitution" is selected to allow the use of a generic version of the drug. To disable, click to clear "Allow Substitution".
  5. Days supply: Enter the prescription days supply.
    Note: For CQM reporting purposes only. The days supply does not populate on a printed prescription.
  6. Effective Date: If applicable, select a date the prescription is effective on. 
  7. Service Location: The default address displays.
    • For eRx enrolled providers, the default address on file with Surescripts displays. Select a different service location from the drop-down as applicable. This option does not require additional eRx enrollments for each service location.
      Note: The service location cannot be changed when renewing/reordering medications or when responding to a renewal response sent by the pharmacy.
  8. Patient Instructions: Select a recommended sigs that automatically populates based on the drug entered or manually enter the patient's instructions.
  9. Reason For Rx: If applicable, enter an ICD-10 code or click Open ICD-10 Browser for more options.
    • To enter a second diagnosis, click Add Another Reason.
  10. Supervising Provider: If applicable, select a supervising provider from the drop-down to send electronically.
    Note: Only active providers who are eRx enrolled will populate in the drop-down list. Supervising provider does not populate on printed prescriptions.
  11. Drug Monograph: Review the recommended dosage for the patient, drug information, warnings, and uses.
    • To hide the drug monograph, click the right arrow to collapse the section. 
Clinical_EPCS_Prescribe.png

Select Pharmacy

Select a pharmacy to view formulary, copay amount, and find coupons.

  1. Pharmacy: By default, the patient's preferred pharmacy is populated. If the patient has multiple preferred pharmacies, click the drop-down to select a different pharmacy from the list.
  2. If necessary, click the drop-down and select Search for pharmacy to find a different pharmacy. The Find a Pharmacy pop-up window opens.
    1. Click to select a pharmacy from the auto generated results based on the patient's zip code or search for a pharmacy.
      • To search for a pharmacy, remove the zip code and enter any of the following search criteria. 
        Tip_Icon.png Tip: Search by a city name or zip code only for broader results.
        • Pharmacy Name: Enter the first 2–3 letters of the pharmacy's name, the whole pharmacy's name, or store number (e.g., CVS, 4825).
        • City: Enter the pharmacy's city.
        • State: Select the pharmacy's state.
        • Zip: Enter the pharmacy's zip code.
        • Phone Number: Enter the pharmacy's phone number.
        • Type: By default, View All is selected. To filter by a pharmacy type, click the drop-down to select Retail, Mail Order, or In House Dispensing.
        • EPCS Certified: By default, pharmacies that are certified for electronic prescriptions for controlled substances (EPCS) display in the search results. To remove the filter, click to clear the selection.
    2. Click Select Pharmacy to add to the prescription.
  3. Pharmacy Instructions: Enter any instructions for the pharmacy; these notes will not appear on the prescription label.
Clinical_EPCS_Pharmacy.png

Patient Cost

View the medication's formulary status, coverage factor, and alternative medications based on the patient's formulary plan.

  1. Insurance: Displays the available copay amount based on the selected plan.
    • Pharmacy Benefit Manager: If multiple plans are available, click the Eligibility drop-down to select a different plan to view the drug coverage and formulary status.
    • Formulary Status: Displays the drug's formulary status with the plan.
      • Non-Formulary: Displays when the drug is not included in the plan.
      • On-Formulary/Non-Preferred: Displays when the drug is on formulary and is not a preferred drug.
      • On-Formulary/Preferred: Displays when the drug is on formulary and is a preferred drug.
      • Formulary Unknown: Displays when coverage information cannot be found or the drug could not be found in the formulary database.
      • Non-reimbursable: Displays when there is no coverage and the patient is responsible for payment.
  2. Coverage Factors: When available, the Quantity Limits, Age Limits, Gender Limits, General Information, Prior Authorization, or Step Therapy details display.
  3. Alternative Medication: When available, a list of alternative drugs within the same therapeutic treatment family displays.
    • To prescribe an alternative drug, click on the medication. The prescription form clears and adds the select medication.
  4. Rx Saver Coupon: Displays the selected pharmacy's discounted rate for the drug. To provide the Rx Saver Coupon to the patient, click to select "Send Via SMS", "Send Via Email", or "Print Coupon". If necessary, enter the applicable mobile phone number or email address.
Clinical_EPCS_PatientCost.png

Validate Prescription

  1. Click Send Medication to electronically send the controlled substance. The New Prescription (Preview) pop-up window opens.
    • To generate a paper prescription, click Print.
  2. Review the Patient, Medication, Pharmacy, and Prescriber details for accuracy.
  3. Click Validate to proceed. The EPCSGold page opens in a new browser.
Clinical_EPCS_Validate.png

Authenticate Prescription

  1. Click to select the prescription.
  2. Select the token Device from the drop down.
  3. Enter the passphrase created during EPCS user registration.
  4. Enter the PIN from the token.
    Tip_Icon.png Tip: If the PIN is about to expire, wait for the next PIN to generate to avoid repeating this step.
  5. Click Sign and Send when finished.
Clinical_PrescribeEPCS_Sign.png